USMLE Forum Archives - USMLE Step 1 - 10
10
drspleen - 03-14-11 23:43
A template DNA sequence 3’-TACTTAATGGCT-5’ mutates into 3’-TACTCTAATGGCT-5’. Which property accounts for the change in the amino acid sequence that is translated from this DNA sequence?
* A. Degenerate
* B. Non-overlapping
* C. Unambiguous
* D. Semi-conservative
* E. None of the above
drspleen - 03-14-11 23:43
A template DNA sequence 3’-TACTTAATGGCT-5’ mutates into 3’-TACTCTAATGGCT-5’. Which property accounts for the change in the amino acid sequence that is translated from this DNA sequence?
* A. Degenerate
* B. Non-overlapping
* C. Unambiguous
* D. Semi-conservative
* E. None of the above
The correct answer and explanation will be available after you answer.
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#1
Re: 10 babbu5508 - 03-19-11 14:09 My answer is: b.
there is a 2 base pair addition into the genetic code but because the genetic code is nonoverlapping it is read frame by frame
#3
Re: 10 sudha2015 - 03-21-11 00:57 My answer is: a.
A template DNA sequence 3’-TACTTAATGGCT-5’ mutates into 3’-TACTCTAATGGCT-5’
degenerative
#4
Re: 10
drspleen - 03-22-11 07:32 B is correct... The mutation is a frameshift - everything from codon 2 onwards is changed. This occurs because of the non-overlapping nature of the genetic code: it’s read from a single starting point in a continuous string.
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