USMLE Forum Archives - USMLE Step 1 - 2225
2225
babbu5508 - 02-28-11 11:23
A donor liver arrives in New York from Chicago 7 hours after harvest. A biopsy is performed on arrival to check for ischemic injury. The sensitive oxidase P450 system is very susceptible to ischemia. In which of the following regions of the liver is this system located?
Options:
A. Bile ducts
B. Intermediate zone
C. "Ito" cells
D. Pericentral vein zone
E. Periportal zone
babbu5508 - 02-28-11 11:23
A donor liver arrives in New York from Chicago 7 hours after harvest. A biopsy is performed on arrival to check for ischemic injury. The sensitive oxidase P450 system is very susceptible to ischemia. In which of the following regions of the liver is this system located?
Options:
A. Bile ducts
B. Intermediate zone
C. "Ito" cells
D. Pericentral vein zone
E. Periportal zone
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#2
Re: 2225
babbu5508 - 03-15-11 11:17 The correct answer is D. The liver can be divided into three zones. Zone 1 is periportal, zone 2 is intermediate (between 1 and 3), and zone 3 is associated with the central vein. Zone 3 contains the P450 oxidase enzyme system and is most sensitive to injury
#3
Re: 2225 sudha2015 - 03-15-11 11:28 A donor liver arrives in New York from Chicago 7 hours after harvest. A biopsy is performed on arrival to check for ischemic injury. The sensitive oxidase P450 system is very susceptible to ischemia. In which of the following regions of the liver is this system located
d
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