USMLE Forum Archives - USMLE Step 1 - 4313
4313
babbu5508 - 06-30-11 20:49
A 48-year-old male presents for a routine evaluation 3 months after starting on an antihypertensive medication. His physical examination is unremarkable and blood pressure is 128/83. Laboratory results reveal the following lipid profile: total cholesterol 280 mg/dL,
HDL 34 mg/dL, LDL 188 mg/dL, and triglycerides 191 mg/dL. His lipid profile was normal prior to beginning his antihypertensive medication. Which of following medications most likely caused the patient's dyslipidemia?
Options:
A. Benazepril
B. Diltiazem
C. Guanfacine
D. Metoprolol
E. Prazosin
babbu5508 - 06-30-11 20:49
A 48-year-old male presents for a routine evaluation 3 months after starting on an antihypertensive medication. His physical examination is unremarkable and blood pressure is 128/83. Laboratory results reveal the following lipid profile: total cholesterol 280 mg/dL,
HDL 34 mg/dL, LDL 188 mg/dL, and triglycerides 191 mg/dL. His lipid profile was normal prior to beginning his antihypertensive medication. Which of following medications most likely caused the patient's dyslipidemia?
Options:
A. Benazepril
B. Diltiazem
C. Guanfacine
D. Metoprolol
E. Prazosin
The correct answer and explanation will be available after you answer.
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#2
Re: 4313
babbu5508 - 06-30-11 22:04 The correct answer is D. The question states that the patient began antihypertensive therapy 3 months earlier and now has elevated total cholesterol, LDL, and triglyceride levels, as well as a low HDL level. Therefore, there is a strong possibility that the antihypertensive medication caused the dyslipidemia. Metoprolol is a beta-adrenergic blocking agent that is known to cause dyslipidemias in patients. None of the other medications are associated with the development of dyslipidemias.
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