Arrhythmias
sudha2015 - 02-04-11 03:52 Bookmark and Share

Question: 1 According to a recent randomized, active-controlled study in 254 adult patients with atrial fibrillation (AF) eligible for cardioversion, vernakalant demonstrated efficacy superior to which drug?
1. Dronedarone
2. Sotalol
3. Amiodarone
4. Propafenone
5. Flecainide

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#1
Re: Arrhythmias
babbu5508 - 06-22-11 16:17

Like other class III antiarrhythmics, vernakalant blocks atrial potassium channels, thereby prolonging repolarization. It differs from typical class III agents by blocking a certain type of potassium channel, the cardiac transient outward potassium current, with increased potency as the heart rate increases

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