USMLE Forum Archives - USMLE Step 2 CK - best drug
best drug
bingousmle - 05-20-10 07:37
A 24-year-old woman presents to the emergency department with a severe, throbbing headache of the right supraorbital area for the past hour. She also complains of nausea and photophobia. She has had similar attacks in the past, often brought on by menstruation. About 45 min ago she took 400 mg of ibuprofen. Which of the following would be the best therapeutic choice at this time?
A: Meperidine, 50 mg intramuscularly
B: Codeine, 60 mg orally
C: Naproxen, 750 mg orally
D: Sumatriptan, 6 mg subcutaneously
E: Verapamil, 300 mg orally
bingousmle - 05-20-10 07:37
A 24-year-old woman presents to the emergency department with a severe, throbbing headache of the right supraorbital area for the past hour. She also complains of nausea and photophobia. She has had similar attacks in the past, often brought on by menstruation. About 45 min ago she took 400 mg of ibuprofen. Which of the following would be the best therapeutic choice at this time?
A: Meperidine, 50 mg intramuscularly
B: Codeine, 60 mg orally
C: Naproxen, 750 mg orally
D: Sumatriptan, 6 mg subcutaneously
E: Verapamil, 300 mg orally
The correct answer and explanation will be available after you answer.
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#2
Re: best drug babbu5508 - 05-20-10 13:56 My answer is: d.
Sumatriptan is structurally similar to serotonin, and is a 5-HT agonist. The specific receptor subtypes it activates are present on the neurons associated with the detection of pain, activation of these inhibitory receptors reduces the activity of these pain neurons and relieves the pain associated with migraine.
#3
Re: best drug
bingousmle - 05-20-10 14:25 @babbu...Sumatriptan is structurally similar to serotonin, and is a 5-HT agonist. The specific receptor subtypes it activates are present on the neurons associated with the detection of pain, activation of these inhibitory receptors reduces the activity of these pain neurons and relieves the pain associated with migraine. a precise explanation...
#4
Re: best drug babbu5508 - 05-21-10 02:28 thank you bingousmle...
The most common side effects of triptans are facial flushing, tingling of the skin, and a sense of tightness around the chest and throat. Other less common side effects include drowsiness, fatigue, and dizziness.
#6
Re: best drug mtniharika - 05-25-10 04:20 My answer is: d.
coronary artery vasospasm, transient myocardial ischemia, myocardial infarction, ventricular tachycardia, and ventricular fibrillation are amongst the serious side effects
#7
Re: best drug bingousmle - 05-25-10 06:25 
posted by babbu5508 on 05-21-10 02:28
thank you bingousmle...
The most common side effects of triptans are facial flushing, tingling of the skin, and a sense of tightness around the chest and throat. Other less common side effects include drowsiness, fatigue, and dizziness.
thank you bingousmle...
The most common side effects of triptans are facial flushing, tingling of the skin, and a sense of tightness around the chest and throat. Other less common side effects include drowsiness, fatigue, and dizziness.
ok..
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