USMLE Forum Archives - USMLE Step 1 - BILE ACID
BILE ACID
agamamber - 02-26-08 12:24
Which of the following results in increased hepatic bile acid synthesis?
1 alcoholic hepatitis
2 bile acid feeding
3 biliary fistula
4 cholestasis
5 high cholesterol diet
agamamber - 02-26-08 12:24
Which of the following results in increased hepatic bile acid synthesis?
1 alcoholic hepatitis
2 bile acid feeding
3 biliary fistula
4 cholestasis
5 high cholesterol diet
Page 1
#1
Re: BILE ACID
radhamesramos - 02-26-08 13:10 It should be a high cholesterol diet. The others diminish the secretion of hepatic bile acid. Well, not sure about alcoholic hepatitis
#3
Re: BILE ACID
sshahraz - 02-26-08 16:36 alcoholic hepatitis cannot be the answer as they might have degrees of cholestasis. I would go with choice 5 but i read a paper on familial hypercholestrolemia and the volume of bile. it says that in many pts with FH the bile volume decreases and it can serve as a risk factor for CAD.
I'd love to see the correct answer!
#4
Re: BILE ACID
agamamber - 02-27-08 11:46 the ans is 3,hepatic bile acid synthesis is subject to -ve feedback regulation by bile acids returning to d liver frm portal circulation.so abnormlities dat interrupt d enterohepatic cycling of bile acids such as bil. fistula vil result in increased bile acid synthesis.
#7
Re: BILE ACID
radhamesramos - 02-27-08 13:00 Thanks For the answer and very good question, congrats!
Page 1






