USMLE Forum Archives - USMLE Step 1 - bm15
bm15
babbu5508 - 03-22-11 22:51
Which of the following enzymes converts androgens to estrogens?
/ A. ALA synthase
/ B. Aromatase
/ C. Branching enzyme
/ D. MethylmalonyI CoA mutase
/ E. PRPP synthetase
babbu5508 - 03-22-11 22:51
Which of the following enzymes converts androgens to estrogens?
/ A. ALA synthase
/ B. Aromatase
/ C. Branching enzyme
/ D. MethylmalonyI CoA mutase
/ E. PRPP synthetase
The correct answer and explanation will be available after you answer.
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#2
Re: bm15
babbu5508 - 03-23-11 14:14 The correct answer is B. The enzyme aromatase is found in adipose tissue (and hence is increased in fat people), muscle, and skin. It acts on androgens to form estrogens by adding double bonds to make a benzene-like ring. It is this enzyme whose activity is relatively increased in liver disease.
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