USMLE Forum Archives - USMLE Step 3 - HEMAT
HEMAT
sudha2015 - 02-17-11 10:05
What is the most common ANY GRADE toxicity associated with first-line dasatinib (100mg once daily) in CP-CML?
A. Nausea
B. Lipase elevation
C. Pleural effusions
D. Rash
E. Muscle/joint pain
sudha2015 - 02-17-11 10:05
What is the most common ANY GRADE toxicity associated with first-line dasatinib (100mg once daily) in CP-CML?
A. Nausea
B. Lipase elevation
C. Pleural effusions
D. Rash
E. Muscle/joint pain
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#1
Re: HEMAT dinmenace - 06-22-11 11:01 Neutropenia and myelosuppression were common toxic effects. Fifteen patients (of 84, ie 18%) in a study developed pleural effusions, which were felt to be a side effect of dasatinib. Some of these patients required thoracentesis or pleurodesis to treat the effusions. Other adverse events included mild to moderate diarrhea, peripheral edema, and headache.
#2
Re: HEMAT babbu5508 - 06-30-11 19:22 Dasatinib is an oral multi- BCR/ABL and Src family tyrosine kinase inhibitor approved for use in patients with chronic myelogenous leukemia (CML) after imatinib treatment and Philadelphia chromosome-positive acute lymphoblastic leukemia
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