USMLE Forum Archives - USMLE Step 2 CK - herbs
herbs
bingousmle - 04-19-10 12:24
You are treating a 75-year-old Caucasian man with benign prostatic hyperplasia (BPH). He would like to consider an herbal medication to control his symptoms. Which of the following is the best option for this
condition?
a. Ginkgo biloba
b. Hypericum (St. John’s wort)
c. Saw palmetto
d. Garlic
e. Glucosamine
bingousmle - 04-19-10 12:24
You are treating a 75-year-old Caucasian man with benign prostatic hyperplasia (BPH). He would like to consider an herbal medication to control his symptoms. Which of the following is the best option for this
condition?
a. Ginkgo biloba
b. Hypericum (St. John’s wort)
c. Saw palmetto
d. Garlic
e. Glucosamine
The correct answer and explanation will be available after you answer.
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#12
Re: herbs
mtniharika - 05-25-10 04:35 may i know what is the medication on this herb and its action which is beneficial in benign prostatic hyperplasia????
#13
Re: herbs
bingousmle - 05-25-10 06:40 
posted by mtniharika on 05-25-10 04:35
may i know what is the medication on this herb and its action which is beneficial in benign prostatic hyperplasia????
may i know what is the medication on this herb and its action which is beneficial in benign prostatic hyperplasia????

http://www.mayoclinic.com/health/saw-palmetto/NS_patient-sawpalmetto
this presentation is a good account on the actions of saw palmetto in general that answers your doubt.... hope that helps niharika...
#15
Re: herbs
babbu5508 - 05-25-10 17:13 aw palmetto appears to possess 5a-reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Hormonal/estrogenic effects have also been reported, as well as direct inhibitory effects on androgen receptors and anti-inflammatory properties.
#16
Re: herbs
bingousmle - 05-28-10 05:30 
posted by babbu5508 on 05-25-10 17:13
aw palmetto appears to possess 5a-reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Hormonal/estrogenic effects have also been reported, as well as direct inhibitory effects on androgen receptors and anti-inflammatory properties.
aw palmetto appears to possess 5a-reductase inhibitory activity (thereby preventing the conversion of testosterone to dihydrotestosterone). Hormonal/estrogenic effects have also been reported, as well as direct inhibitory effects on androgen receptors and anti-inflammatory properties.

yeah this has been one of the proposed mechanisms of action of saw palmetto for treatment of benign prostate hyperplasia..
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