USMLE Forum Archives - USMLE Step 2 CK - HIV q
HIV q
HIV - 12-31-07 12:38
A 24-year-old man comes to the clinic complaining of flu-like symptoms. For the past 10 days, he has had diffuse myalgias, low-grade fevers, headache, and occasional nausea and vomiting. He reports being generally healthy in the past, though a review of his chart reveals that he was treated for gonorrhea 4 weeks ago. Exam is remarkable for a diffuse, tender lymphadenopathy as well as two small, painful mucocutaneous ulcers in hisoropharynx. On further discussion with the patient, he reveals that he has numerous HIV risk factors, including intravenous drug use and sex with commercial sex workers. Which of the following is the most appropriate HIV test for this patient
A) CD4+ T-cell count
B) ELISA for HIV antibody
C) HIV RNA level
D) P24 antigen serology
E) Western blot
HIV - 12-31-07 12:38
A 24-year-old man comes to the clinic complaining of flu-like symptoms. For the past 10 days, he has had diffuse myalgias, low-grade fevers, headache, and occasional nausea and vomiting. He reports being generally healthy in the past, though a review of his chart reveals that he was treated for gonorrhea 4 weeks ago. Exam is remarkable for a diffuse, tender lymphadenopathy as well as two small, painful mucocutaneous ulcers in hisoropharynx. On further discussion with the patient, he reveals that he has numerous HIV risk factors, including intravenous drug use and sex with commercial sex workers. Which of the following is the most appropriate HIV test for this patient
A) CD4+ T-cell count
B) ELISA for HIV antibody
C) HIV RNA level
D) P24 antigen serology
E) Western blot
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#3
Re: HIV q 8401glacieres - 01-11-08 12:56 B------------ELISA for antibody is the most appropriate test for HIV. If +ve should be read as reactive test and not be labled as positive unless confirmed by WESTERN BLOT. Antibody testing is highly sensitive test but with low specificity ie chances of labling the person as positive when he is not, therefore a confirmatory test is done. The idea of any screening test is high sensitivity and specificity.
P24 antigen assays are not used in this patient as he doesn't have any risk factors like direct innoculation.Another eg where P24 can be used is in VERTICAL transmission, which is not the case either.
#4
Re: HIV q drsri117 - 01-11-08 13:12 b. elisa
thts the first test to be done in a diagnostic work up for hiv.
rest all follow up for conformation!!
#6
Re: HIV q ammulufy - 06-30-10 21:03 Since he has all d predisposing risk factors of a probably HIV infection.....directly one can go on to western blotting instead of ELISA test....hence I go wid E.
#7
Re: HIV q bingousmle - 06-30-10 21:26 the patient has signs and symptoms of HIV infection the best way to go about this is to forst get an elisa and then if positive get a western blot
#8
Re: HIV q babbu5508 - 07-10-10 02:59 B) ELISA for HIV antibody..in view of his multiple risk factors for hiv infection, to be screened by ELISA nd if positive, confirmed by western blot
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