USMLE Forum Archives - USMLE Step 2 CK - ID 3
ID 3
conym5 - 11-20-09 22:50
A man who has a penile chancre appears in a hospital’s emergency
service. The VDRL test is negative. The most appropriate course of action
for the physician in charge would be to ???????
conym5 - 11-20-09 22:50
A man who has a penile chancre appears in a hospital’s emergency
service. The VDRL test is negative. The most appropriate course of action
for the physician in charge would be to ???????
The correct answer and explanation will be available after you answer.
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#4
Re: ID 3
conym5 - 11-23-09 07:21 nonspecific
tests such as the RPR and VDRL, and specific tests such as the
FTA, TPHA (Treponema pallidum hemagglutination test), and the MHTP
(microhemagglutination-T. pallidum). The difference is that the nonspecific
tests use a cross-reactive antigen known as cardiolipin, while the
specific tests use a T. pallidum antigen. Although the nonspecific tests are
sensitive, they lack specificity and often cross-react in patients who have
diabetes, hepatitis, infectious mononucleosis, or who are pregnant. Some
patients, especially those with autoimmune diseases, will have both nonspecific
(RPR) and specific tests (FTA) positive.
#28
Re: ID 3 ammulufy - 03-14-10 20:32 My answer is: c.
Penile chancre is very much diagnostic of Syphilis that too primary syphilis......however I am confused between a n c..... I am not sure whther further confirmation is required or not....however its a well known fact dat false positive tests are very common.....therefore I go with c.
#36
Re: ID 3 mtniharika - 04-29-10 08:48 My answer is: c.
As VDRL is a non-specific test for syphilis, specific tests for syphilis like TPHI or FTA tests should be performed
#37
Re: ID 3 babbu5508 - 05-23-10 02:57 My answer is: c.
false negative for syphilis with VDRL test....the next step would be to do a better test or confirmatory test like FTA or TPHA or dark field microscopy
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