USMLE Step 2 CK - ITP
ITP
mohhaider - 09-19-08 08:13
Ideopathic Thrompcytopenic Purpura is caused by ideopathic antibody that bind the platlets and leading to phagocytosis of these platelets by macrophages.The following is true about ITP EXCEPT :
(A) Low platelets count
(B) Normal creatinine level
(C) Splenomegaly
(D) Increased bone marrow megakaryocytes
(E) Associated with CLL
mohhaider - 09-19-08 08:13
Ideopathic Thrompcytopenic Purpura is caused by ideopathic antibody that bind the platlets and leading to phagocytosis of these platelets by macrophages.The following is true about ITP EXCEPT :
(A) Low platelets count
(B) Normal creatinine level
(C) Splenomegaly
(D) Increased bone marrow megakaryocytes
(E) Associated with CLL
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#2
Re: ITP
mohhaider - 09-27-08 11:42 The answer is c .Normal spleen is what found in ITP .Normal creatinine is expected here and differntiate it from HUS and TTP .
#6
Re: ITP sackatdoc - 09-28-08 09:31 yes i read yesterday only, if we see enlarged spleen, we should doubt our diagnosis of ITP, ALSO in management of ITP WHICH IS NOT REPONDING, SPLENECTOMY IS TREATMENT OF CHOICE, though spleen is not enlarged, the normal sized spleen is causing the platlets to be phagocytosed, so once removed, no thrombocytopenia.
#8
Re: ITP mohhaider - 10-17-08 00:00 Yes Youngdoctor ,there is an association between ITP and CLL ,lymphoma,HIV,and connective tissue disease.The refrence Kaplan internal medicine lecture notes for STEP 2 CK .
#9
Re: ITP sackatdoc - 10-18-08 03:23 yes,in CLL, there is ITP, reference also from book called diagnosis and therapeutics
#10
Re: ITP mohhaider - 10-20-08 05:27 Yes ,some associations can not be explained logically right now ,may be in the future there is explanation ,so we should accept them as they are mentioned in many refrences .
#11
Re: ITP moazzamhyder - 11-18-08 07:57 answer is c no splenomegaly and a new drug has come to increase platelet count in itp
#12
Re: ITP kingofhearts - 11-19-08 04:23 dear docs i would like to add that spleenomegaly is seen in CHRONIC CASES OF IDIOPATHIC THROMBOCYTOPEBIC PURPURA...... so i would like to go with b...please correct me if i am wrong .....
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