USMLE Forum Archives - USMLE Step 3 - malaria
malaria
bingousmle - 07-26-10 07:05
A 19-year-old man plans on traveling through Central America by bus. He comes to clinic interested intravel advice and any vaccinations he may need. He has no medical history and takes no medicines. In addition to DEET and mosquito netting, which of the following recommendations would be important for prophylaxis against malaria?
A. Atovaquone
B. Chloroquine
C. Doxycycline
D. Mefloquine
E. Primaquine
bingousmle - 07-26-10 07:05
A 19-year-old man plans on traveling through Central America by bus. He comes to clinic interested intravel advice and any vaccinations he may need. He has no medical history and takes no medicines. In addition to DEET and mosquito netting, which of the following recommendations would be important for prophylaxis against malaria?
A. Atovaquone
B. Chloroquine
C. Doxycycline
D. Mefloquine
E. Primaquine
The correct answer and explanation will be available after you answer.
Page 1
#3
Re: malaria
bingousmle - 07-27-10 01:21 My answer is: b.
Malaria prophylaxis recommendations vary by region the recommended malaria prophylaxis for Central America is chloroquine. In contrast, due to chloroquine resistance of falciparum malaria, prophylaxis in India and
most areas in Africa is with atovaquone/proguanil, doxycycline, or mefloquine
#4
Re: malaria babbu5508 - 07-27-10 03:10 My answer is: b.
Chloroquine, proguanil, mefloquine, and doxycycline are suppressive prophylactics. This means that they are only effective at killing the malaria parasite once it has entered the erythrocytic stage of its life cycle, and therefore have no effect until the liver stage is complete. That is why these prophylactics must continue to be taken for four weeks after leaving the area of risk.
Page 1