USMLE Forum Archives - USMLE Step 2 CK - MCQ on Phosphoribosyl PP Synthase
MCQ on Phosphoribosyl PP Synthase
sudha2015 - 01-06-11 10:16
What is commonly the first clinical finding in the mild type of phosphoribosylpyrophosphate synthetase (PRS) superactivity?
A.URINARY STONE
B.GOUTY ARTHRITIS
C.SENSRINEURAL HEARING LOSS
D.HYPOTONIA
sudha2015 - 01-06-11 10:16
What is commonly the first clinical finding in the mild type of phosphoribosylpyrophosphate synthetase (PRS) superactivity?
A.URINARY STONE
B.GOUTY ARTHRITIS
C.SENSRINEURAL HEARING LOSS
D.HYPOTONIA
Page 1
#2
Re: MCQ on Phosphoribosyl PP Synthase babbu5508 - 01-12-11 12:53 What is commonly the first clinical finding in the mild type of phosphoribosylpyrophosphate synthetase (PRS) superactivity?
B.GOUTY ARTHRITIS
not sure though...
#3
Re: MCQ on Phosphoribosyl PP Synthase
sudha2015 - 01-12-11 12:58 a.
Uric acid crystalluria or a urinary stone is commonly the first clinical finding in mild PRS superactivity, followed later by gouty arthritis if serum urate concentration is not controlled. Variable combinations of sensorineural hearing loss, hypotonia, and ataxia observed in the severe type of PRS superactivity are not usually present in the mild type.
Page 1