USMLE Forum Archives - USMLE Step 1 - MCQs on Muscle Pathology 6
MCQs on Muscle Pathology 6
paresha - 02-06-11 13:05
Question 15 A 9 year old girl gets tired easily but is still able to perform nomal daily activities. Through young adulthood, she continues to exhibit mild generalized muscle weakness. On physical examination, she has motor strength 2/5 in all extremities along with hypotonia. Reflexes are normal. She has no myalgias. A deltoid biopsy shows muscle fibers with numerous rod-shaped intracytoplasmic inclusions. She is most likely to have:
A An autoimmune disease
B Lower motor neuron disease
C Muscular dystrophy
D A congenital myopathy
E Myophosphorylase deficiency
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Question 16 A 35-year-old female had a diagnosis of polymyositis made with a muscle biopsy. Following a course of corticosteroid therapy, she continues to have muscular weakness, particular in proximal muscles. The serum creatine kinase (CK) is only 41 U/L, and an electromyogram demonstrates no myopathic changes. These findings most strongly suggest:
A Treatment failure
B Upper motor neuron disease
C Corticosteroid-induced myopathy
D McArdle's disease
E Duchenne muscular dystrophy
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Question 17 Which one of the following histologic findings on muscle biopsy would be most indicative of an active polymyositis:
A Marked fiber hypertrophy
B Many fibers undergoing degeneration and regeneration
C Grouping of atrophic fibers
D Extensive endomysial and perimysial fibrosis
E Subsarcolemmal glycogen deposition
paresha - 02-06-11 13:05
Question 15 A 9 year old girl gets tired easily but is still able to perform nomal daily activities. Through young adulthood, she continues to exhibit mild generalized muscle weakness. On physical examination, she has motor strength 2/5 in all extremities along with hypotonia. Reflexes are normal. She has no myalgias. A deltoid biopsy shows muscle fibers with numerous rod-shaped intracytoplasmic inclusions. She is most likely to have:
A An autoimmune disease
B Lower motor neuron disease
C Muscular dystrophy
D A congenital myopathy
E Myophosphorylase deficiency
NEXT QUESTION - - INDEX OF QUESTIONS - - EXAM MENU
Question 16 A 35-year-old female had a diagnosis of polymyositis made with a muscle biopsy. Following a course of corticosteroid therapy, she continues to have muscular weakness, particular in proximal muscles. The serum creatine kinase (CK) is only 41 U/L, and an electromyogram demonstrates no myopathic changes. These findings most strongly suggest:
A Treatment failure
B Upper motor neuron disease
C Corticosteroid-induced myopathy
D McArdle's disease
E Duchenne muscular dystrophy
NEXT QUESTION - - INDEX OF QUESTIONS - - EXAM MENU
Question 17 Which one of the following histologic findings on muscle biopsy would be most indicative of an active polymyositis:
A Marked fiber hypertrophy
B Many fibers undergoing degeneration and regeneration
C Grouping of atrophic fibers
D Extensive endomysial and perimysial fibrosis
E Subsarcolemmal glycogen deposition
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#3
Re: MCQs on Muscle Pathology 6 babbu5508 - 02-08-11 03:08 A deltoid biopsy shows muscle fibers with numerous rod-shaped intracytoplasmic inclusions. She is most likely to have:
E Myophosphorylase deficiency
#5
Re: MCQs on Muscle Pathology 6 babbu5508 - 02-22-11 10:01 A 35-year-old female had a diagnosis of polymyositis made with a muscle biopsy. Following a course of corticosteroid therapy, she continues to have muscular weakness, particular in proximal muscles. The serum creatine kinase (CK) is only 41 U/L, and an electromyogram demonstrates no myopathic changes. These findings most strongly suggest:
C Corticosteroid-induced myopathy
Page 1