USMLE Forum Archives - USMLE Step 1 - mdp4
mdp4
babbu5508 - 05-31-11 23:57
Which of the following genes is involved in the pathogenesis of this disease?
/ A. ATP7B, Iocated on chromosome 13
/ B. D23116, Iocated on chromosome 2q33-q34
/ C. IT15, Iocated on chromosome 4p
/ D. N-acetyI-transferase 2, Iocated on chromosome 8
/ E. 6p21, Iocated on chromosome 6
babbu5508 - 05-31-11 23:57
Which of the following genes is involved in the pathogenesis of this disease?
/ A. ATP7B, Iocated on chromosome 13
/ B. D23116, Iocated on chromosome 2q33-q34
/ C. IT15, Iocated on chromosome 4p
/ D. N-acetyI-transferase 2, Iocated on chromosome 8
/ E. 6p21, Iocated on chromosome 6
The correct answer and explanation will be available after you answer.
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#1
Re: mdp4 dinmenace - 06-01-11 21:48 My answer is: c.
The HTT gene is located on the short arm of chromosome 4 at 4p16.3. HTT contains a sequence of three DNA bases—cytosine-adenine-guanine (CAG)—repeated multiple times (i.e. ... CAGCAGCAG ...), known as a trinucleotide repeat
#4
Re: mdp4 riya10 - 06-03-11 13:15 
posted by babbu5508 on 05-31-11 23:57
Which of the following genes is involved in the pathogenesis of this disease?
/ A. ATP7B, Iocated on chromosome 13
/ B. D23116, Iocated on chromosome 2q33-q34
/ C. IT15, Iocated on chromosome 4p
/ D. N-acetyI-transferase 2, Iocated on chromosome 8
/ E. 6p21, Iocated on chromosome 6
Which of the following genes is involved in the pathogenesis of this disease?
/ A. ATP7B, Iocated on chromosome 13
/ B. D23116, Iocated on chromosome 2q33-q34
/ C. IT15, Iocated on chromosome 4p
/ D. N-acetyI-transferase 2, Iocated on chromosome 8
/ E. 6p21, Iocated on chromosome 6
hi babbu, thats very good, you are sharing questions, plz if possible try to write down explainations too, thanz
#5
Re: mdp4
babbu5508 - 06-16-11 01:29 The correct answer is C. Huntington disease is a genetic disorder of the central nervous system, and is inherited as an autosomal dominant condition. In affected individuals, one gene of the gene pair is not functioning properly and "dominates" the other working gene. The HD gene, called IT15, is located on chromosome 4p.
#6
Re: mdp4 babbu5508 - 06-16-11 01:29 posted by riya10 on 06-03-11 13:15
hi babbu, thats very good, you are sharing questions, plz if possible try to write down explainations too, thanz
hi babbu, thats very good, you are sharing questions, plz if possible try to write down explainations too, thanz
here come the explanations..i had to search some of them so the delay in posting..
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