USMLE Forum Archives - USMLE Step 1 - Microbiology
Microbiology
mohhaider - 08-05-08 00:20
A57-year-old man seeks medical attention for the recent appearance of numerous, large, fluid-filled, cutaneous blisters. These involve the face, scalp, neck, and axillae. Manual pressure to the skin results in epidermal separation.These changes are most likely the result of which of the following?
(A) autoimmune disorder
(B) bacterial infection
(C) dietary deficiency
(D) exposure to a chemical toxin
(E) local ischemia
mohhaider - 08-05-08 00:20
A57-year-old man seeks medical attention for the recent appearance of numerous, large, fluid-filled, cutaneous blisters. These involve the face, scalp, neck, and axillae. Manual pressure to the skin results in epidermal separation.These changes are most likely the result of which of the following?
(A) autoimmune disorder
(B) bacterial infection
(C) dietary deficiency
(D) exposure to a chemical toxin
(E) local ischemia
Page 1
#3
Re: Pathology
mohhaider - 08-05-08 17:35 Sorry the answer is A
Pemphigus vulgaris is an autoimmune disorder.The autoantibodies are directed against keratinocyte antigens with subsequent dyshesion and fluid-filled blister formation .
Manual pressure to the skin results in epidermal separation =Nickolisky sign not found in Bulous pemphigoid
#4
Re: Microbiology babbu5508 - 07-28-10 04:21 i think it is pemphigus vulgaris, an autoimmune disorder...with numerous, large, fluid-filled, cutaneous blisters. These involve the face, scalp, neck, and axillae. Manual pressure to the skin results in epidermal separation.
Page 1