USMLE Forum Archives - USMLE Step 1 - mpp9
mpp9
babbu5508 - 05-31-11 23:39
The woman decides that she prefers an attempt at medical control before deciding whether or not to have surgery. Which of the following would be the most appropriate pharmacotherapy?
/ A. AIIopurinol
/ B. Danazol
/ C. Diazepam
/ D. Digoxin
/ E. Tetracycline
babbu5508 - 05-31-11 23:39
The woman decides that she prefers an attempt at medical control before deciding whether or not to have surgery. Which of the following would be the most appropriate pharmacotherapy?
/ A. AIIopurinol
/ B. Danazol
/ C. Diazepam
/ D. Digoxin
/ E. Tetracycline
The correct answer and explanation will be available after you answer.
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#1
Re: mpp9
dinmenace - 06-01-11 11:45 My answer is: b.
Danazol (Danocrine) and gestrinone are suppressive steroids with some androgenic activity. Both agents inhibit the growth of endometriosis but their use remains limited as they may cause hirsutism and voice changes.
#2
Re: mpp9
babbu5508 - 06-16-11 01:09 The correct answer is B. Depending upon the severity of the disease, therapy for endometriosis can involve pain medication, pharmacologic manipulation of the implants, surgical or laser ablation of individual implants, or surgical removal of affected pelvic organs. Drug therapy for endometriosis can include combination estrogen/progestin oral contraceptives, progestins, steroids such as danazol, or GnRH agonists such as nafarelin and leuprolide.
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