USMLE Forum Archives - USMLE Step 1 - Pathology 41
Pathology 41
TheOne - 11-26-06 16:46
Which of the following is a major interleukin produced by CD4+ T helper 1 (TH1) lymphocytes?
A. IL-1
B. IL-2
C. IL-4
D. IL-6
E. IL-8
TheOne - 11-26-06 16:46
Which of the following is a major interleukin produced by CD4+ T helper 1 (TH1) lymphocytes?
A. IL-1
B. IL-2
C. IL-4
D. IL-6
E. IL-8
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#3
Re: Pathology 41
TheOne - 11-30-06 20:24 Explanation: The correct answer is B. IL-2 produced by TH1 cells stimulates natural killer (NK) cells and CD8+ T cytotoxic lymphocytes and combines with IL-2 receptors on the TH1 cells to cause "self-stimulation". IL-2 is also involved in downregulating CD4+ T helper 2 lymphocytes. IL-1 (choice A) is derived from macrophages and is a major inflammatory molecule. IL-4 (choice C) is derived from CD4 + T helper 2 cells. It acts to downregulate CD4 + TH1 cells and allows class switching to IgE. IL-6 (choice D) is derived from macrophages. This molecule stimulates acute phase protein production by the liver, as well as the production of other opsonizing molecules. IL-8 (choice E) is derived from macrophages and is a major chemotactic molecule for neutrophils.
#4
Re: Pathology 41 galaxy - 05-28-10 02:32 Which of the following is a major interleukin produced by CD4+ T helper 1 (TH1) lymphocytes?
B. Interleukin 2 are by CD4 T lymphocytes
#5
Re: Pathology 41 babbu5508 - 06-21-10 15:41 B. IL-2 hepls in body's natural response to microbial infection and in discriminating between foreign (non-self) and self
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