USMLE Forum Archives - USMLE Step 3 - Pr Med: Polio
Pr Med: Polio
meduploader - 05-16-09 13:37
Indications
Health care workers in close contact with patients excreting wild poliovirus or who handle lab specimens from such patients.
Travelers to developing countries
In immunocompromised patients ( HIV), if polio vaccine is indicated – give IPV. Household members and nursing personnel in close contact with immunocompromised patients should not receive OPV ( They should be given IPV)
Contraindications
IPV:
Pregnancy
Anaphylactic allergy to streptomycin or neomycin.
OPV:
If the Vaccine recipient or if prospective vaccine recepient’s household contact is immunodeficient or immunosuppressed (including HIV infection)
Pregnancy - only a relative contraindication. If immediate protection is needed, use OPV.
Anaphylactic allergy to neomycin or streptomycin
meduploader - 05-16-09 13:37
Indications
Health care workers in close contact with patients excreting wild poliovirus or who handle lab specimens from such patients.
Travelers to developing countries
In immunocompromised patients ( HIV), if polio vaccine is indicated – give IPV. Household members and nursing personnel in close contact with immunocompromised patients should not receive OPV ( They should be given IPV)
Contraindications
IPV:
Pregnancy
Anaphylactic allergy to streptomycin or neomycin.
OPV:
If the Vaccine recipient or if prospective vaccine recepient’s household contact is immunodeficient or immunosuppressed (including HIV infection)
Pregnancy - only a relative contraindication. If immediate protection is needed, use OPV.
Anaphylactic allergy to neomycin or streptomycin
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Re: Pr Med: Polio mtniharika - 10-05-09 15:28 A major concern about the oral polio vaccine (OPV) is its known ability to revert to a form that can achieve neurological infection and cause paralysis.Clinical disease, including paralysis, caused by vaccine-derived poliovirus (VDPV) is indistinguishable from that caused by wild polioviruses.This is believed to be a rare event, but outbreaks of vaccine-associated paralytic poliomyelitis (VAPP) have been reported, and tend to occur in areas of low coverage by OPV, presumably because the OPV is itself protective against the related outbreak strain.
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