Re: Scleroderma renal crisis
sabiraghauri - 06-07-09 11:54

I think Ace inhibitors can be used for both issues.

Re: Scleroderma renal crisis
zkadhem - 06-07-09 11:56

yes,
Although the patient has renal failure(which is a contraindication for the use of ACEI in other patients), yet the drug of choice for this patient with scleroderma renal crisis is acei

Re: Scleroderma renal crisis
conym5 - 06-17-09 02:41

ACE inhibitors

Re: Scleroderma renal crisis
mtniharika - 11-22-09 03:33

Blood pressure control with angiotensin-converting enzyme (ACE) inhibitors with gradual reduction of malignant hypertension is the cornerstone of treatment. Other agents such as calcium channel blocking agents may be added. Renal dialysis may even be required. It is important that the blood pressure be lowered gradually (ie, avoid use of intravenous nitroprusside or labetalol) and do not let the patient develop hypovolemia. An excellent review summarizes pathogenesis and treatment

Re: Scleroderma renal crisis
babbu5508 - 02-23-11 02:09

Patients with diffuse, rapid skin involvement have the highest risk (approximately 20-25%) of developing scleroderma renal crisis. Renal crisis occurs in about 10% of all patients with systemic sclerosis.
Renal crisis presents as accelerated hypertension, oliguria, headache, dyspnea, edema, and rapidly rising serum creatinine levels.

Re: Scleroderma renal crisis
sudha2015 - 03-31-11 12:56

control with angiotensin-converting enzyme (ACE) inhibitors with gradual reduction of malignant hypertension is the cornerstone of treatment

Re: Scleroderma renal crisis
babbu5508 - 03-31-11 13:03

Scleroderma renal crisis is characterized by:

Abrupt onset of moderate to severe hypertension
Urine sediment that is normal or reveals only mild proteinuria with few cells or casts
Progressive renal failure

Re: Scleroderma renal crisis
rahul721 - 04-05-11 00:01

Acei