USMLE Forum Archives - USMLE Step 2 CK - substance abuse 2
substance abuse 2
conym5 - 11-16-09 12:30
A 50-year-old male physician with a history of meperidine addiction
arrive at the emergency room by ambulance. His respiration is
shallow and infrequent, his pupils are constricted, and he is stuporous.
Q. Another symptom of meperidine intoxication, especially in the
context of chronic use is
conym5 - 11-16-09 12:30
A 50-year-old male physician with a history of meperidine addiction
arrive at the emergency room by ambulance. His respiration is
shallow and infrequent, his pupils are constricted, and he is stuporous.
Q. Another symptom of meperidine intoxication, especially in the
context of chronic use is
The correct answer and explanation will be available after you answer.
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#2
Re: substance abuse 2
conym5 - 11-16-09 17:28 Severe opiate intoxication is associated with respiratory
depression, stupor or coma, and, sometimes, pulmonary edema. Less severe intoxication is associated with slurred speech, drowsiness, and impaired memory or attention.Meperidine intoxication in a chronic
user is often complicated by delirium or seizures due to the accumulation of normeperidine, a toxic metabolite with cerebral irritant properties.
#30
Re: substance abuse 2 mtniharika - 04-29-10 08:54 My answer is: d.
Severe symptoms
Severe hyperpyrexia
Seizures
CNS depression
Coma
Cardiorespiratory depression
Malignant hyperthermia
Muscle rigidity
#31
Re: substance abuse 2 babbu5508 - 05-23-10 02:43 My answer is: d.
Convulsive seizures sometimes observed in patients receiving parenteral pethidine on a chronic basis have been attributed to accumumulation in plasma of the metabolite norpethidine
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