Sudden change!!!
laparotomy - 01-06-08 14:23 Bookmark and Share

A 62 year old male presents with constipation for 3 days and mild to moderate abdominal discomfort. His past history is significant for a triple bypass operation 5 years ago. His lab values are normal. An overly cautious surgical resident admits the patient. The next day he becomes confused. Urgent bloods are taken with the following results: ALT 1100, Bilirubin 5, Creatinine 7, BUN 72.
What is your diagnosis?

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#1
Re: Sudden change!!!
laparotomy - 01-07-08 00:19

Does anyone have any idea?

#2
Re: Sudden change!!!
InSitu - 01-07-08 00:51

sounds like hepatic encephalopathy.

#3
Re: Sudden change!!!
laparotomy - 01-07-08 14:43

Obviously it is a hepatorenal failure, but what is the cause?

#4
Re: Sudden change!!!
TheOne - 01-07-08 15:16

Constipation?

#5
Re: Sudden change!!!
zeemoon5 - 01-08-08 08:33

not enough in case. Does it has to do with the triple bypass...

#6
Re: Sudden change!!!
laparotomy - 01-08-08 11:01

That is some serious constipation if it caused a hepatorenal failure...
Okay I will give you the options

A.Dehydration causing prerenal failure
B.Ascending Cholangitis
C.Fulminant viral hepatitis
D. Ischemic hepatitis
E. Drug induced hepatitis

#7
Re: Sudden change!!!
InSitu - 01-08-08 11:53

Thanks a lot Laparotomy....very good case

#8
Re: Sudden change!!!
TheOne - 01-08-08 15:35

D. Ischemic hepatitis

I think i understood the question in a wrong way, constipation should be avoided in patients with critical hepatic function cause it may lead to hepatic encephalopathy, right?

#9
Re: Sudden change!!!
drsim07 - 01-12-08 23:52

interesting
thanks for putting up such a question

#10
Re: Sudden change!!!
laparotomy - 01-14-08 05:09

Exactly the one that is why lactulose is a treatment to of hepatic encephalopathy and also prophilactic to prevent it...

#11
Re: Sudden change!!!
laparotomy - 01-14-08 05:10

Anyway the answer is ischemic hepatitis.... congrats to those that got it right.

#12
Re: Sudden change!!!
ammulufy - 07-03-10 20:52

Bcos he developed dose symptoms after being admitted to d hospital....probably its drug induced hepatitis,i.e d.

#13
Re: Sudden change!!!
babbu5508 - 07-07-10 21:31

Urgent bloods are taken with the following results: ALT 1100, Bilirubin 5, Creatinine 7, BUN 72.....hepatorenal syndrome

#14
Re: Sudden change!!!
bingousmle - 07-12-10 05:32

constipation leading to hepatic encephalopathy.. though the patient should have pre existing decompensated hepatic failure which is not mentioned

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