USMLE Forum Archives - USMLE Step 3 - Which of the following drugs is contrain
Which of the following drugs is contrain
meduploader - 05-11-09 07:13 Bookmark and Share

A 27-year-old HIV-seropositive Haitian man develops cough, fever, and weight loss. Chest x-ray reveals
a cavitary lesion in the left upper lobe. Sputum culture is found to be smear-positive and, subsequently,
culture-positive for Mycobacterium tuberculosis. He is hospitalized and placed in isolation. Medications
include zidovudine, lamivudine, and indinavir, as well as trimethoprim-sulfamethoxazole.
Which of the following drugs is contraindicated in this patient?






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#1
Re: Which of the following drugs is cont
harry206 - 05-11-09 07:24

My answer is: a.

#2
Re: Which of the following drugs is cont
bingousmle - 05-11-09 09:52

My answer is: c.

#3
Re: Which of the following drugs is cont
usmlefever3 - 05-12-09 03:01

My answer is: a.


rifampin interacts with protease inhibitors,deviradine ,nevirapine and efavirenz by induction of metabolism decreasing levels of these drugs.
in this case ,rifampin interacts with TMP/SMX decreasing it's level
Zidovudine also interacts with TMP/SMX by causing bone marrow supression

#4
Re: Which of the following drugs is cont
mtniharika - 09-22-09 13:23

My answer is: a.

#5
Re: Which of the following drugs is cont
lisjan - 11-06-09 20:16

My answer is: e.

#6
Re: Which of the following drugs is cont
1811166 - 12-29-09 02:48

My answer is: a.

#7
Re: Which of the following drugs is cont
conym5 - 12-29-09 08:35

My answer is: a.


May lead to loss of virologic response and possible resistance to CRIXIVAN or to the class of protease inhibitors or other coadministered antiretroviral agents.

#8
Re: Which of the following drugs is cont
souvikadhikari - 12-29-09 12:21

My answer is: a.

#9
Re: Which of the following drugs is cont
ysemak - 12-29-09 19:37

My answer is: a.

#10
Re: Which of the following drugs is cont
medusmle01 - 12-30-09 07:24

My answer is: a.

#11
Re: Which of the following drugs is cont
demolition - 12-30-09 07:53

My answer is: e.

#12
Re: Which of the following drugs is cont
drthapa - 12-30-09 11:36

My answer is: a.

#13
Re: Which of the following drugs is cont
zoah2005 - 12-30-09 12:45

My answer is: a.

#14
Re: Which of the following drugs is cont
sabiraghauri - 12-30-09 14:38

My answer is: c.

#15
Re: Which of the following drugs is cont
amaniagz - 12-30-09 17:16

My answer is: c.

#16
Re: Which of the following drugs is cont
aaronhurowitz - 01-01-10 23:25

My answer is: e.

#17
Re: Which of the following drugs is cont
fas148 - 01-02-10 09:15

My answer is: e.

#18
Re: Which of the following drugs is cont
reksarma - 01-26-10 17:53

My answer is: c.

#19
Re: Which of the following drugs is cont
chike66 - 02-03-10 01:19

My answer is: d.

#20
Re: Which of the following drugs is cont
rejuvicell - 02-03-10 09:04

My answer is: a.

#21
Re: Which of the following drugs is cont
freedom - 02-27-10 18:38

My answer is: e.

#22
Re: Which of the following drugs is cont
shahra - 02-28-10 06:43

My answer is: e.

#23
Re: Which of the following drugs is cont
katamoto - 03-24-10 00:50

My answer is: a.

#24
Re: Which of the following drugs is cont
residencyrace - 05-31-10 15:01

My answer is: a.

#25
Re: Which of the following drugs is cont
bobby - 06-08-10 22:12

My answer is: a.

#26
Re: Which of the following drugs is cont
dopamine - 06-09-10 22:04

My answer is: d.

#27
Re: Which of the following drugs is cont
chinni17 - 06-10-10 14:51

My answer is: a.

#28
Re: Which of the following drugs is cont
abuzic - 07-24-10 23:50

My answer is: a.

#29
Re: Which of the following drugs is cont
victoria12 - 07-26-10 15:55

My answer is: a.

#30
Re: Which of the following drugs is cont
babbu5508 - 07-28-10 05:07

My answer is: a.


i think this because rifampicin is an enzyme inducer and here being given with anti retroviral drugs.....therefore to be thought of

#31
Re: Which of the following drugs is cont
bmnnbm - 07-30-10 15:36

My answer is: a.

#32
Re: Which of the following drugs is cont
fudge15019 - 10-07-10 23:38

My answer is: a.

#33
Re: Which of the following drugs is cont
bobudevi - 10-08-10 00:52

My answer is: a.

#34
Re: Which of the following drugs is cont
123munir - 10-08-10 14:41

My answer is: d.

#35
Re: Which of the following drugs is cont
robbyj32 - 02-13-11 11:51

My answer is: c.

#36
Re: Which of the following drugs is cont
dinmenace - 06-30-11 23:08

My answer is: c.

#37
Re: Which of the following drugs is cont
visionary235 - 07-12-11 23:10

My answer is: d.

#38
Re: Which of the following drugs is cont
rahirouba - 11-08-11 18:16

My answer is: a.

#39
Re: Which of the following drugs is cont
anjalistha - 11-09-11 17:36

My answer is: e.

#40
Re: Which of the following drugs is cont
godzfav8490 - 11-10-11 13:10

My answer is: a.

#41
Re: Which of the following drugs is cont
jamiljajr - 11-10-11 20:50

My answer is: d.

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